Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 14/20 | 0.72 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.72 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | GART | P22102 | 1/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25745979 | 0.86 | FPR2 (0.73) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494613 | 0.85 | FPR2 (0.72) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL21494659 | 0.84 | FPR2 (1.00) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL21494660 | 0.84 | FPR2 (1.00) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL30106804 | 0.84 | FPR2 (1.00) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL21494644 | 0.81 | FPR2 (0.69) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL21494720 | 0.80 | FPR2 (1.00) | FPR2MTHFD1MTHFD2AKR1B1 | |
| SCHEMBL21494722 | 0.80 | FPR2 (1.00) | FPR2MTHFD1MTHFD2AKR1B1 | |
| SCHEMBL30106791 | 0.80 | FPR2 (1.00) | FPR2MTHFD1MTHFD2AKR1B1 | |
| SCHEMBL21494747 | 0.79 | FPR2 (0.67) | FPR2MTHFD1MTHFD2GART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781554-B1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FOER MEDICINSK FORSKNING (SE) | 2023-06-28 | — | — | EP | disclosed |