Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.65 |
| ▸ | JAK1 | P23458 | 6/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.65 |
| ▸ | STAT3 | P40763 | 1/20 | 0.65 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30465857 | 0.95 | TYK2 (0.58) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL31095902 | 0.92 | TYK2 (0.56) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL25671619 | 0.92 | TYK2 (0.56) | TYK2JAK1KCNH2STAT3JAK2 | |
| Lithium SCHEMBL31017478 | 0.91 | TYK2 (0.56) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL29883117 | 0.91 | TYK2 (0.77) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL29232108 | 0.91 | TYK2 (0.77) | TYK2JAK1KCNH2STAT3JAK2 | |
| Lithium Ion SCHEMBL31096018 | 0.91 | TYK2 (0.57) | TYK2JAK1KCNH2STAT3JAK2 | |
| Lithium Ion SCHEMBL27199285 | 0.91 | TYK2 (0.57) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL29232081 | 0.90 | TYK2 (0.59) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL29883180 | 0.90 | TYK2 (0.59) | TYK2JAK1KCNH2STAT3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |