Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 17/20 | 0.77 |
| ▸ | JAK1 | P23458 | 6/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.77 |
| ▸ | STAT3 | P40763 | 1/20 | 0.77 |
| ▸ | JAK2 | O60674 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29883117 | 1.00 | TYK2 (0.77) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL25749407 | 0.91 | TYK2 (0.65) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL29882982 | 0.89 | TYK2 (0.61) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL25748842 | 0.88 | TYK2 (0.62) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL30465876 | 0.88 | TYK2 (0.62) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL27290626 | 0.87 | TYK2 (0.64) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL30465857 | 0.86 | TYK2 (0.58) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL29882748 | 0.85 | TYK2 (0.60) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL29232098 | 0.85 | TYK2 (0.60) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL29232021 | 0.84 | TYK2 (0.61) | TYK2JAK1KCNH2STAT3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197196-B | TYK2 inhibitor and application thereof | 扬子江药业集团有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115197196-A | TYK2 inhibitor and application thereof | 扬子江药业集团有限公司 | 2022-10-18 | — | — | CN | disclosed |