⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751189 | 0.87 | — | — | |
| SCHEMBL25207064 | 0.87 | — | — | |
| SCHEMBL30424120 | 0.87 | — | — | |
| SCHEMBL25752443 | 0.85 | — | — | |
| SCHEMBL30424381 | 0.85 | TEAD1 (0.33) | — | |
| SCHEMBL25206654 | 0.85 | TEAD1 (0.33) | — | |
| SCHEMBL25747815 | 0.82 | CREBBP (0.31) | — | |
| SCHEMBL25748159 | 0.76 | CCNA2 (0.33) | — | |
| SCHEMBL25202799 | 0.73 | — | — | |
| SCHEMBL30423562 | 0.73 | NR3C1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202984-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2023-06-29 | — | — | US | disclosed |