Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703940 | 1.00 | GSK3B (0.39) | GSK3BDYRK1ASCN9ACYP17A1ATR | |
| SCHEMBL24517615 | 0.88 | MAPKAPK2 (0.38) | GSK3BDYRK1ASCN9ACYP17A1ATR | |
| SCHEMBL29112758 | 0.84 | CNR2 (0.41) | GSK3BDYRK1ASCN9ACYP17A1ATR | |
| SCHEMBL29604131 | 0.83 | ATR (0.40) | GSK3BDYRK1ASCN9ACYP17A1ATR | |
| SCHEMBL23107173 | 0.83 | ATR (0.40) | GSK3BDYRK1ASCN9ACYP17A1ATR | |
| SCHEMBL29971093 | 0.81 | CYP17A1 (0.39) | GSK3BDYRK1ASCN9ACYP17A1ATR | |
| SCHEMBL15091115 | 0.81 | CYP17A1 (0.39) | GSK3BDYRK1ASCN9ACYP17A1ATR | |
| SCHEMBL6999990 | 0.81 | MAPKAPK2 (0.38) | GSK3BDYRK1ASCN9ACYP17A1ATR | |
| SCHEMBL25751246 | 0.81 | ATR (0.43) | GSK3BDYRK1ASCN9ACYP17A1ATR | |
| SCHEMBL16992870 | 0.80 | ATR (0.45) | GSK3BDYRK1ASCN9ACYP17A1ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |