SCHEMBL25751563

SCHEMBL25751563

CCOC(=O)C1CCC=NC1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.41
GAA P10253 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PDK1 Q15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1414061 0.76 MAPT (0.51) ALDH1A1MAPTMEN1KMT2A
SCHEMBL34475901 0.76 MAPT (0.51) ALDH1A1MAPTMEN1KMT2A
SCHEMBL9834573 0.75 MAPT (0.44) ALDH1A1MAPTMEN1KMT2A
SCHEMBL2539787 0.74 MAPT (0.46) ALDH1A1MAPTMEN1KMT2A
SCHEMBL18439839 0.74 ALDH1A1 (0.51) ALDH1A1MAPTMEN1KMT2A
SCHEMBL234449 0.74 ALDH1A1 (0.47) ALDH1A1MAPTMEN1KMT2A
SCHEMBL11979742 0.74 ALDH1A1 (0.51) ALDH1A1MAPTMEN1KMT2A
SCHEMBL29427 0.73
SCHEMBL18367 0.73 ALDH1A1 (0.68) ALDH1A1MAPTMEN1KMT2A
SCHEMBL2417773 0.73 MAPT (0.45) ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3860561-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2023-06-21 EP disclosed