Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | VDR | P11473 | 5/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24226063 | 0.86 | ESR1 (0.47) | ESR1VDRTHRATHRBKLF10 | |
| SCHEMBL17013416 | 0.84 | ESR1 (0.45) | ESR1VDRTHRATHRBKLF10 | |
| SCHEMBL25846204 | 0.84 | SLC6A2 (0.47) | ESR1VDRKLF10ACE2SHBG | |
| SCHEMBL18355808 | 0.82 | ESR1 (0.44) | ESR1THRATHRBKLF10SHBG | |
| SCHEMBL16116515 | 0.82 | ESR1 (0.44) | ESR1THRATHRBKLF10ACE2 | |
| SCHEMBL16116520 | 0.82 | ESR1 (0.44) | ESR1THRATHRBKLF10ACE2 | |
| SCHEMBL16576651 | 0.81 | ESR1 (0.42) | ESR1THRATHRBKLF10ACE2 | |
| SCHEMBL25846210 | 0.80 | ESR1 (0.37) | ESR1VDRKLF10ACE2SHBG | |
| SCHEMBL16154154 | 0.80 | PDCD1 (0.45) | ESR1MAPTALDH1A1CYP3A4GAA | |
| SCHEMBL16576698 | 0.78 | ESR1 (0.40) | ESR1THRATHRBKLF10ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |