Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751730 | 0.84 | ESR1 (0.48) | BLMKDM4EALDH1A1CYP1A2POLB | |
| SCHEMBL25846208 | 0.81 | ESR1 (0.35) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL25846222 | 0.81 | CYP1A2 (0.62) | SLC6A2TAAR1BLMKDM4EALDH1A1 | |
| SCHEMBL25846223 | 0.81 | ESR1 (0.35) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL25846211 | 0.81 | CYP3A4 (0.46) | BLMKDM4EALDH1A1CYP1A2POLB | |
| SCHEMBL25846210 | 0.77 | ESR1 (0.37) | VDRKLF10ACE2SHBGESR1 | |
| SCHEMBL2140136 | 0.74 | SLC6A2 (0.57) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL29366879 | 0.74 | EGFR (0.47) | KDM4EMAPTHSD17B10EGFRRECQL | |
| SCHEMBL63126 | 0.74 | EGFR (0.47) | KDM4EMAPTHSD17B10EGFRRECQL | |
| SCHEMBL13953779 | 0.74 | CNR1 (0.50) | CYP3A4MAPTALOX15TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702383-B2 | Methods for producing D-α-methyldopa | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702383-B2 | Methods for producing D-α-methyldopa | AMPD2, AMPD3, AMPD1 | SLC6A2 476/4885HTR2A 54/4885SLC6A4 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.