Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.79 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999371 | 0.88 | STAT3 (1.00) | STAT3CTDSP1SIRT5ALDH1A1MEN1 | |
| SCHEMBL2000416 | 0.84 | STAT3 (0.74) | STAT3CTDSP1SIRT5MEN1KMT2A | |
| SCHEMBL1998361 | 0.83 | STAT3 (0.78) | STAT3CTDSP1SIRT5MAPTALDH1A1 | |
| SCHEMBL2002782 | 0.81 | STAT3 (0.69) | STAT3CTDSP1SIRT5ALDH1A1MEN1 | |
| SCHEMBL12359466 | 0.80 | STAT3 (0.81) | STAT3CTDSP1SIRT5ALDH1A1MEN1 | |
| SCHEMBL5870583 | 0.80 | KMT2A (0.62) | STAT3MAPTALDH1A1KMT2ACA2 | |
| SCHEMBL10826368 | 0.77 | STAT3 (0.63) | STAT3CTDSP1SIRT5ALDH1A1MEN1 | |
| SCHEMBL31249645 | 0.77 | STAT3 (1.00) | STAT3CTDSP1SIRT5ALDH1A1MEN1 | |
| SCHEMBL18428753 | 0.77 | PSMD10 (0.50) | STAT3MAPTALDH1A1KMT2ACA2 | |
| SCHEMBL4456216 | 0.77 | STAT3 (1.00) | STAT3CTDSP1SIRT5ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212568-A1 | MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS | UNIVERSITY OF ROCHESTER | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212568-A1 | MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS | MYT1, STAT3, MYC | STAT3 2/4885CTDSP1 3329/4885SIRT5 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.