SCHEMBL25752441

SCHEMBL25752441

COC(=O)c1ccc(N(Cc2ccc(C3CCCCC3)cc2)C(=O)c2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 8/20 0.76
GCGR P47871 6/20 0.49
GIPR P48546 5/20 0.47
PTGES O14684 3/20 0.46
ALOX5 P09917 3/20 0.46
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LPAR1 Q92633 1/20 0.43
LPAR5 Q9H1C0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17083303 0.92 STAT3 (0.79) STAT3GCGRGIPRPTGESALOX5
SCHEMBL17083301 0.91 STAT3 (0.83) STAT3GCGRGIPRPTGESALOX5
SCHEMBL17083302 0.90 STAT3 (0.79) STAT3GCGRPTGESALOX5
SCHEMBL15668402 0.89 STAT3 (0.75) STAT3
SCHEMBL15668215 0.89 STAT3 (0.84) STAT3
SCHEMBL25403432 0.86 STAT3 (0.76) STAT3GCGRGIPRPTGESALOX5
SCHEMBL17076888 0.86 STAT3 (1.00) STAT3GCGRGIPRPTGESALOX5
Phosphine SCHEMBL20327798 0.86 STAT3 (0.75) STAT3GCGRGIPRPTGESALOX5
SCHEMBL17076921 0.86 STAT3 (1.00) STAT3GCGRGIPRPTGESALOX5
SCHEMBL17083305 0.85 STAT3 (0.79) STAT3GCGRGIPRPTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212568-A1 MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS UNIVERSITY OF ROCHESTER 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212568-A1 MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS MYT1, STAT3, MYC STAT3 2/4885GCGR 2792/4885GIPR 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.