Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795814 | 0.86 | HPGD (0.46) | HPGDTP53GPR119TDP1RECQL | |
| SCHEMBL24745481 | 0.86 | HPGD (0.46) | HPGDTP53GPR119TDP1RECQL | |
| SCHEMBL728912 | 0.86 | USP2 (0.49) | HPGDGPR119ALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL23384349 | 0.85 | HPGD (0.45) | HPGDTP53GPR119TDP1RECQL | |
| SCHEMBL309857 | 0.85 | HPGD (0.45) | HPGDTP53GPR119TDP1RECQL | |
| SCHEMBL1479749 | 0.83 | ACHE (0.48) | HPGDTP53GPR119TDP1RECQL | |
| SCHEMBL4987189 | 0.82 | HPGD (0.51) | HPGDTP53GPR119TDP1RECQL | |
| SCHEMBL7368909 | 0.81 | SMN1; SMN2 (0.43) | HPGDTP53GPR119EPHX1KDM4E | |
| SCHEMBL24744816 | 0.81 | HPGD (0.43) | HPGDTP53GPR119TDP1RECQL | |
| SCHEMBL8671449 | 0.81 | CHRM2 (0.43) | HPGDTP53GPR119TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122481-A2 | CHEMICAL LINKERS | SIGMA-ALDRICH CO. LLC (US) | 2023-06-29 | — | — | WO | disclosed |