Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2575306 | 0.90 | MET (0.81) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2570742 | 0.88 | MET (0.69) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL3318351 | 0.87 | MET (0.71) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL12121792 | 0.87 | MET (0.58) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL28922896 | 0.87 | MET (0.70) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL30948878 | 0.86 | MET (0.67) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22109395 | 0.86 | MET (0.67) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2574063 | 0.86 | MET (0.81) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2571074 | 0.85 | MET (0.65) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2572667 | 0.84 | MET (0.81) | METCYP2C9PDE3BPDE3APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018383-B1 | TRIAZOLOPYRAZINE DERIVATIVES USEFUL AS ANTI-CANCER AGENTS | PFIZER PROD INC (US) | 2011-11-09 | — | — | EP | disclosed |