Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25623016 | 1.00 | BACE1 (0.31) | BACE1MEN1POLBKMT2AEPHX2 | |
| SCHEMBL24036884 | 1.00 | BACE1 (0.31) | BACE1MEN1POLBKMT2AEPHX2 | |
| SCHEMBL25753641 | 0.92 | EPHX2 (0.32) | EPHX2 | |
| SCHEMBL24036536 | 0.92 | EPHX2 (0.32) | EPHX2 | |
| SCHEMBL25753649 | 0.88 | HTR2C (0.34) | BACE1MEN1POLBKMT2A | |
| SCHEMBL24036539 | 0.88 | HTR2C (0.34) | BACE1MEN1POLBKMT2A | |
| SCHEMBL24036770 | 0.88 | POLB (0.35) | BACE1MEN1POLBKMT2A | |
| SCHEMBL25753611 | 0.88 | POLB (0.35) | BACE1MEN1POLBKMT2A | |
| SCHEMBL24036896 | 0.87 | MEN1 (0.32) | MEN1KMT2AEPHX2 | |
| SCHEMBL25753629 | 0.87 | MEN1 (0.32) | MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | UBE CORPORATION (JP) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | DHFR, DPYD, CYP2D6 | BACE1 3067/4885MEN1 431/4885POLB 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.