⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754399 | 0.85 | HSD17B10 (0.36) | — | |
| SCHEMBL25754392 | 0.82 | HTT (0.35) | — | |
| SCHEMBL25754401 | 0.76 | — | — | |
| SCHEMBL22646536 | 0.76 | — | — | |
| SCHEMBL25754398 | 0.75 | HTT (0.46) | — | |
| SCHEMBL1954600 | 0.74 | CYP3A4 (0.37) | — | |
| SCHEMBL25754406 | 0.71 | HTT (0.32) | — | |
| SCHEMBL28058598 | 0.70 | MEN1 (0.32) | — | |
| SCHEMBL11957412 | 0.69 | — | — | |
| SCHEMBL9291335 | 0.69 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |