Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19741578 | 0.85 | MEN1 (0.33) | MEN1KMT2ANR1H2NR1H3MAPT | |
| SCHEMBL15266412 | 0.79 | — | — | |
| SCHEMBL15266411 | 0.79 | — | — | |
| SCHEMBL16001326 | 0.79 | — | — | |
| SCHEMBL17292829 | 0.79 | NR1H2 (0.35) | MEN1KMT2ANR1H2NR1H3MAPT | |
| SCHEMBL15961085 | 0.77 | — | — | |
| SCHEMBL16769767 | 0.76 | — | — | |
| SCHEMBL15878857 | 0.75 | ESR1 (0.33) | MAPTESR1ESR2 | |
| SCHEMBL12341670 | 0.75 | ESR1 (0.33) | MAPTESR1ESR2 | |
| SCHEMBL331185 | 0.75 | ESR1 (0.33) | MAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048977-B2 | Organosilicon polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-01 | — | — | US | claimed |
| US-20090069525-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-03-12 | — | — | US | claimed |
| US-8048977-B2 | Organosilicon polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-01 | — | — | US | disclosed |
| US-20090069525-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-03-12 | — | — | US | disclosed |