SCHEMBL19741578

SCHEMBL19741578

C=CC[Si](C)(C)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
MAPT P10636 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2575440 0.85 MEN1 (0.33) MEN1KMT2ANR1H2NR1H3MAPT
SCHEMBL13822356 0.81 ALDH1A1 (0.30)
SCHEMBL4867088 0.79
SCHEMBL17292829 0.79 NR1H2 (0.35) MEN1KMT2ANR1H2NR1H3MAPT
SCHEMBL17816335 0.78 ESR1 (0.35) MAPTESR1ESR2
SCHEMBL17816338 0.76 ESR1 (0.34) MAPTESR1ESR2
SCHEMBL8464699 0.76 ESR1 (0.31) ESR1ESR2
SCHEMBL28604831 0.75 ESR1 (0.33) MAPTESR1ESR2
SCHEMBL912509 0.75 ESR1 (0.33) MAPTESR1ESR2
SCHEMBL3317837 0.74 NR1H2 (0.37) MEN1KMT2ANR1H2NR1H3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458499-B1 FLAME RETARDANT RESIN COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2026-03-25 EP disclosed
CN-109642029-B Flame-retardant resin composition 莫门蒂夫性能材料股份有限公司 2022-02-18 CN disclosed
US-10266648-B2 Flame retardant resin composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-04-23 US disclosed
CN-109642029-A Fire-proof resin composition 莫门蒂夫性能材料股份有限公司 2019-04-16 CN disclosed
US-20170369644-A1 FLAME RETARDANT RESIN COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2017-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10266648-B2 Flame retardant resin composition RER1, GAR1, AFF1 MEN1 4571/4885KMT2A 729/4885NR1H2 425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.