Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.44 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15125681 | 0.85 | KIF11 (0.52) | KIF11CYP2D6PSEN1PSEN2APH1B | |
| SCHEMBL15125661 | 0.85 | KIF11 (0.52) | KIF11CYP2D6PSEN1PSEN2APH1B | |
| SCHEMBL1908532 | 0.83 | POLB (0.46) | KIF11CYP2D6PSEN1PSEN2APH1B | |
| SCHEMBL31555358 | 0.83 | CYP1A2 (0.52) | CYP2D6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7515433 | 0.80 | SREBF1 (0.46) | KIF11CYP2D6PSEN1PSEN2APH1B | |
| SCHEMBL14015421 | 0.79 | SREBF2 (0.50) | CYP2D6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13273291 | 0.79 | SREBF2 (0.50) | CYP2D6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11182769 | 0.79 | SREBF2 (0.50) | CYP2D6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11254418 | 0.79 | SREBF2 (0.50) | CYP2D6PSEN1PSEN2APH1BNCSTN | |
| Bromide SCHEMBL28698106 | 0.78 | SREBF1 (0.45) | KIF11CYP2D6PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |