Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 15/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 14/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 14/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24246865 | 1.00 | GNAO1 (0.46) | GNAO1GNAI3GNAI1EPHX1CCR2 | |
| SCHEMBL18609539 | 1.00 | GNAO1 (0.46) | GNAO1GNAI3GNAI1EPHX1CCR2 | |
| SCHEMBL20417319 | 1.00 | GNAO1 (0.46) | GNAO1GNAI3GNAI1EPHX1CCR2 | |
| SCHEMBL21180109 | 1.00 | GNAO1 (0.46) | GNAO1GNAI3GNAI1EPHX1CCR2 | |
| SCHEMBL24435761 | 1.00 | GNAO1 (0.46) | GNAO1GNAI3GNAI1EPHX1CCR2 | |
| SCHEMBL22224479 | 0.98 | GNAO1 (0.44) | GNAO1GNAI3GNAI1EPHX1CCR2 | |
| SCHEMBL19375748 | 0.98 | GNAO1 (0.44) | GNAO1GNAI3GNAI1EPHX1CCR2 | |
| SCHEMBL23745311 | 0.96 | GNAO1 (0.43) | GNAO1GNAI3GNAI1EPHX1CCR2 | |
| SCHEMBL22224480 | 0.96 | GNAO1 (0.42) | GNAO1GNAI3GNAI1EPHX1CCR2 | |
| SCHEMBL23059321 | 0.94 | GNAO1 (0.41) | GNAO1GNAI3GNAI1EPHX1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |