⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25755035 | 0.90 | — | — | |
| SCHEMBL25755021 | 0.86 | SLC6A2 (0.31) | — | |
| SCHEMBL25754799 | 0.86 | SLC6A2 (0.39) | — | |
| SCHEMBL25755032 | 0.85 | HTR4 (0.30) | — | |
| SCHEMBL25755018 | 0.85 | SLC6A2 (0.32) | — | |
| SCHEMBL25755026 | 0.85 | SLC6A2 (0.32) | — | |
| SCHEMBL25754795 | 0.82 | SLC6A2 (0.35) | — | |
| SCHEMBL25755019 | 0.82 | SLC6A2 (0.31) | — | |
| SCHEMBL25754790 | 0.81 | SLC6A2 (0.35) | — | |
| SCHEMBL25755030 | 0.81 | SLC6A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |