Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 8/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25756096 | 1.00 | TK1 (0.55) | TK1POLBLMNATSHRALB | |
| SCHEMBL25700742 | 0.91 | TK1 (0.50) | TK1POLBLMNATSHRALB | |
| SCHEMBL25700727 | 0.87 | TK1 (0.60) | TK1POLB | |
| SCHEMBL25756099 | 0.87 | TK1 (0.60) | TK1POLB | |
| SCHEMBL25752637 | 0.87 | TK1 (0.60) | TK1POLB | |
| SCHEMBL25129409 | 0.85 | TK1 (0.51) | TK1POLBLMNATSHRALB | |
| SCHEMBL29967409 | 0.81 | TK1 (0.53) | TK1POLBNT5M | |
| SCHEMBL29967685 | 0.81 | TK1 (0.53) | TK1POLBNT5M | |
| SCHEMBL7038203 | 0.79 | TK1 (0.53) | TK1POLBNT5M | |
| SCHEMBL7201324 | 0.79 | TK1 (0.60) | TK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |