SCHEMBL25756464

SCHEMBL25756464

COC(=O)[C@H]1Cc2c([nH]c3ccccc23)CN1C(=O)OC(C)(C)C

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 7/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29582353 1.00 CYP19A1 (0.72) CYP19A1
SCHEMBL24380346 1.00 CYP19A1 (0.72) CYP19A1
SCHEMBL16750308 1.00 CYP19A1 (0.72) CYP19A1
SCHEMBL8243497 0.89 ACE (0.67) CYP19A1
SCHEMBL677552 0.89 ACE (0.67) CYP19A1
SCHEMBL29666098 0.89 ACE (0.67) CYP19A1
SCHEMBL5880416 0.89 ACE (0.67) CYP19A1
SCHEMBL26312410 0.89 CYP19A1 (0.57) CYP19A1
SCHEMBL15112498 0.88 ACHE (0.57) CYP19A1
SCHEMBL15112500 0.88 ACHE (0.57) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023109926-A1 SPIROOXINDOLE COMPOUND AND USE THEREOF IN PREPARATION OF PROTEASE INHIBITOR AS ANTIVIRAL DRUG 南京药石科技股份有限公司 2023-06-22 WO disclosed