Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.56 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463182 | 0.87 | GRN (0.68) | GRNSORT1PSMB5CCR1SMN1; SMN2 | |
| SCHEMBL12043743 | 0.75 | GRN (0.67) | GRNSORT1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29093009 | 0.73 | GRN (0.64) | GRNSORT1PSMB5CCR1SMN1; SMN2 | |
| SCHEMBL29093013 | 0.73 | GRN (0.64) | GRNSORT1PSMB5CCR1SMN1; SMN2 | |
| SCHEMBL7463178 | 0.73 | GRN (0.68) | GRNSORT1PSMB5CCR1SMN1; SMN2 | |
| SCHEMBL24283499 | 0.72 | GRN (1.00) | GRNSORT1PSMB5CCR1SMN1; SMN2 | |
| SCHEMBL7468748 | 0.72 | ALDH1A1 (0.54) | GRNSORT1CCR1SMN1; SMN2NPC1 | |
| SCHEMBL30606650 | 0.72 | GRN (1.00) | GRNSORT1PSMB5CCR1SMN1; SMN2 | |
| SCHEMBL24283500 | 0.72 | GRN (1.00) | GRNSORT1PSMB5CCR1SMN1; SMN2 | |
| SCHEMBL29092497 | 0.71 | GRN (0.62) | GRNSORT1PSMB5CCR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109926-A1 | SPIROOXINDOLE COMPOUND AND USE THEREOF IN PREPARATION OF PROTEASE INHIBITOR AS ANTIVIRAL DRUG | 南京药石科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |