Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GLB1 | P16278 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25773972 | 0.95 | MEN1 (0.42) | MEN1KMT2AALDH1A1GBA1GNAI3 | |
| SCHEMBL4345371 | 0.89 | MEN1 (0.41) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL7593545 | 0.75 | MEN1 (0.50) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL8034075 | 0.75 | KMT2A (0.55) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL4424409 | 0.75 | MEN1 (0.45) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL13985052 | 0.73 | MEN1 (0.40) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL18434093 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL24051990 | 0.71 | MEN1 (0.42) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL7044546 | 0.71 | MEN1 (0.42) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL27400590 | 0.71 | MEN1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |