Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860930 | 1.00 | GSK3B (0.40) | GSK3BDYRK1AITGA4ITGB7CACNA1H | |
| SCHEMBL30895136 | 0.92 | GSK3B (0.36) | GSK3BDYRK1AITGA4ITGB7CACNA1H | |
| SCHEMBL31017447 | 0.92 | GSK3B (0.36) | GSK3BDYRK1AITGA4ITGB7CACNA1H | |
| SCHEMBL25750456 | 0.85 | GSK3B (0.37) | GSK3BDYRK1AITGA4ITGB7PIK3CD | |
| SCHEMBL31017361 | 0.85 | GSK3B (0.37) | GSK3BDYRK1AITGA4ITGB7PIK3CD | |
| SCHEMBL25753072 | 0.85 | PIK3CD (0.42) | GSK3BDYRK1AATRBRD9PIK3CD | |
| SCHEMBL25672474 | 0.85 | MAPK1 (0.39) | GSK3BDYRK1AITGA4ITGB7CACNA1H | |
| SCHEMBL30895142 | 0.84 | MAPK1 (0.38) | GSK3BDYRK1AITGA4ITGB7MEN1 | |
| SCHEMBL31017347 | 0.84 | MAPK1 (0.38) | GSK3BDYRK1AITGA4ITGB7MEN1 | |
| SCHEMBL25753440 | 0.84 | GSK3B (0.38) | GSK3BDYRK1APIK3CDABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401516-A | TYK2 inhibitors, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |