Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895142 | 1.00 | MAPK1 (0.38) | MAPK1MAOAMAOBGSK3BDYRK1A | |
| SCHEMBL25750456 | 0.90 | GSK3B (0.37) | MAPK1GSK3BDYRK1AKDM4ENPC1 | |
| SCHEMBL31017361 | 0.90 | GSK3B (0.37) | MAPK1GSK3BDYRK1AKDM4ENPC1 | |
| SCHEMBL25672474 | 0.88 | MAPK1 (0.39) | MAPK1GSK3BDYRK1AKDM4EABL1 | |
| SCHEMBL25758055 | 0.86 | KDM4E (0.36) | GSK3BDYRK1AKDM4ENPC1RAB9A | |
| SCHEMBL30895063 | 0.86 | MAPK1 (0.38) | MAPK1GSK3BDYRK1AABL1SRC | |
| SCHEMBL27199684 | 0.85 | MAPK1 (0.43) | MAPK1MAOAMAOBPDE10AKDM4E | |
| SCHEMBL30860930 | 0.84 | GSK3B (0.40) | MAPK1GSK3BDYRK1AABL1HTT | |
| SCHEMBL25756633 | 0.84 | GSK3B (0.40) | MAPK1GSK3BDYRK1AABL1HTT | |
| SCHEMBL30895022 | 0.84 | HTR2A (0.36) | MAPK1GSK3BDYRK1AABL1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401516-A | TYK2 inhibitors, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-26 | — | — | CN | disclosed |