Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 3/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.39 |
| ▸ | RXRA | P19793 | 6/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25756972 | 0.90 | IP6K1 (0.41) | IP6K1NR1H2NR1H3RXRAIMPDH2 | |
| SCHEMBL24380252 | 0.86 | IMPDH2 (0.41) | NR1H2NR1H3RXRAIMPDH2PTPN1 | |
| SCHEMBL24446810 | 0.85 | IMPDH2 (0.40) | NR1H2NR1H3RXRAIMPDH2PTPN1 | |
| SCHEMBL24451648 | 0.85 | IMPDH2 (0.40) | IP6K1NR1H2NR1H3RXRAIMPDH2 | |
| SCHEMBL24454022 | 0.85 | IMPDH2 (0.40) | IP6K1NR1H2NR1H3RXRAIMPDH2 | |
| SCHEMBL25756975 | 0.83 | IP6K1 (0.37) | IP6K1 | |
| SCHEMBL29616653 | 0.83 | BACE1 (0.53) | NR1H2NR1H3RXRAIMPDH2BACE1 | |
| SCHEMBL6523576 | 0.83 | BACE1 (0.53) | NR1H2NR1H3RXRAIMPDH2BACE1 | |
| SCHEMBL3724868 | 0.83 | BACE1 (0.53) | NR1H2NR1H3RXRAIMPDH2BACE1 | |
| SCHEMBL6523965 | 0.83 | BACE1 (0.53) | NR1H2NR1H3RXRAIMPDH2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109926-A1 | SPIROOXINDOLE COMPOUND AND USE THEREOF IN PREPARATION OF PROTEASE INHIBITOR AS ANTIVIRAL DRUG | 南京药石科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |