SCHEMBL25757

SCHEMBL25757

[c]1ccc2occcc1-2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297554 0.86 ALDH1A1 (0.43)
SCHEMBL208436 0.80
SCHEMBL6988965 0.74 ALDH1A1 (0.38)
SCHEMBL14782784 0.74 PIK3R1 (0.45)
SCHEMBL10849820 0.74 PIK3R1 (0.45)
SCHEMBL9598318 0.71 ALDH1A1 (0.34)
SCHEMBL10848154 0.71 ALDH1A1 (0.37)
SCHEMBL21295842 0.69 POLB (0.32)
SCHEMBL1799678 0.68 ALDH1A1 (0.63)
SCHEMBL450165 0.67 ALDH1A1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2569 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49118-E1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US claimed
CN-112390811-B Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-03-04 CN claimed
CN-114057711-A Anthracene ketone spiro derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-02-18 CN claimed
CN-107556298-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-12-21 CN claimed
CN-107586290-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-05-11 CN claimed
CN-112390811-A Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2021-02-23 CN claimed
CN-110551054-A maleimide derivative, and preparation method and application thereof TECHNICAL INST PHYSICS & CHEMISTRY CAS 2019-12-10 CN claimed
US-10294246-B2 Substituted boronic acids and boronate esters as immunoproteasome inhibitors MERCK PATENT GMBH (DE) 2019-05-21 US claimed
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-05-07 US claimed
CN-106892915-B Organic compound, organic electroluminescence device and its application 南京高光半导体材料有限公司 2019-02-22 CN claimed
EP-0824524-A1 ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE PHARMACIA &amp; UPJOHN COMPANY (US) 1998-02-25 EP claimed
CN-1144526-A Thiazolidines and oxazolidines substituted by pyridine ring and their use a hypoglycemic agents NISSAN CHEMICAL IND LTD (JP) 1997-03-05 CN claimed
EP-0751944-A1 THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-01-08 EP claimed
WO-1996035678-A1 ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE PHARMACIA & UPJOHN COMPANY (US) 1996-11-14 WO claimed
CN-1134697-A Pyrimidine-sulfanyl and alkyl ether compounds UPJOHN CO (US) 1996-10-30 CN claimed
EP-0728130-A1 PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS PHARMACIA &amp; UPJOHN COMPANY (US) 1996-08-28 EP claimed
WO-1995026347-A1 THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1995-10-05 WO claimed
WO-1995013267-A1 PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS THE UPJOHN COMPANY (US) 1995-05-18 WO claimed
EP-0572449-A1 (AMIDOMETHYL)NITROGEN HETEROCYCLIC ANALGESICS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-12-08 EP claimed
WO-1992012128-A1 (AMIDOMETHYL)NITROGEN HETEROCYCLIC ANALGESICS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1992-07-23 WO claimed