Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.63 |
| ▸ | SRC | P12931 | 7/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220694 | 0.84 | EGFR (0.57) | EGFRSRCMTNR1AMTNR1BKDM4E | |
| SCHEMBL27478799 | 0.81 | EGFR (0.69) | EGFRSRCKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL27640062 | 0.80 | EGFR (0.67) | EGFRSRCKDM4EALDH1A1HPGD | |
| SCHEMBL7127236 | 0.80 | EGFR (0.71) | EGFRSRCKDM4EALDH1A1 | |
| SCHEMBL25757058 | 0.79 | EGFR (0.54) | EGFRSRCMTNR1AMTNR1BCHRNB2 | |
| SCHEMBL18715184 | 0.77 | EGFR (0.48) | EGFRSRCMTNR1AMTNR1BKDM4E | |
| SCHEMBL11084371 | 0.77 | KDM4E (0.57) | EGFRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27761686 | 0.75 | EGFR (0.64) | EGFRSRCCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL22118373 | 0.73 | EGFR (0.65) | EGFRSRCKDM4EALDH1A1HPGD | |
| SCHEMBL31404858 | 0.73 | EGFR (0.65) | EGFRSRCKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109926-A1 | SPIROOXINDOLE COMPOUND AND USE THEREOF IN PREPARATION OF PROTEASE INHIBITOR AS ANTIVIRAL DRUG | 南京药石科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |