Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.54 |
| ▸ | SRC | P12931 | 3/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905352 | 0.80 | EGFR (0.58) | EGFRSRCMTNR1AMTNR1BMAPT | |
| SCHEMBL25757057 | 0.79 | EGFR (0.63) | EGFRSRCMTNR1AMTNR1BCHRNB2 | |
| SCHEMBL7355774 | 0.78 | EGFR (0.60) | EGFRSRCMAPT | |
| SCHEMBL14220694 | 0.73 | EGFR (0.57) | EGFRSRCMTNR1AMTNR1B | |
| SCHEMBL7127236 | 0.72 | EGFR (0.71) | EGFRSRCMAPT | |
| SCHEMBL29224605 | 0.72 | MTNR1A (0.50) | MTNR1AMTNR1BCTSLCTSSCTSK | |
| SCHEMBL26996502 | 0.72 | MAPT (0.48) | CTSLTACR1TP53MAPTCTSS | |
| SCHEMBL27478799 | 0.71 | EGFR (0.69) | EGFRSRC | |
| SCHEMBL29224727 | 0.71 | CA2 (0.49) | MTNR1AMTNR1BCTSSCTSK | |
| SCHEMBL27761686 | 0.71 | EGFR (0.64) | EGFRSRCCHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109926-A1 | SPIROOXINDOLE COMPOUND AND USE THEREOF IN PREPARATION OF PROTEASE INHIBITOR AS ANTIVIRAL DRUG | 南京药石科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |