SCHEMBL25757544

SCHEMBL25757544

CCCn1nc(C(F)(F)F)c2cccnc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.43
PDE4A P27815 3/20 0.40
PDE4B Q07343 3/20 0.40
PDE4C Q08493 3/20 0.40
PDE4D Q08499 3/20 0.40
RET P07949 1/20 0.38
CNR1 P21554 2/20 0.37
CNR2 P34972 2/20 0.37
MEN1 O00255 2/20 0.36
MAPK1 P28482 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
CRHBP P24387 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
CRHR2 Q13324 1/20 0.36
PTGDR2 Q9Y5Y4 2/20 0.36
PDE10A Q9Y233 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25759526 0.88 ELANE (0.49) ELANEL3MBTL1PDE4APDE4BPDE4C
SCHEMBL15491616 0.79 ELANE (0.53) ELANEL3MBTL1MAPTPTGDR2
SCHEMBL20552850 0.78 L3MBTL1 (0.63) L3MBTL1PDE4APDE4BPDE4CPDE4D
SCHEMBL15484830 0.78 ELANE (0.55) ELANEL3MBTL1MEN1KMT2AMAPT
SCHEMBL15492976 0.77 KMT2A (0.50) ELANEL3MBTL1MEN1KMT2ATSHR
SCHEMBL12299464 0.74 L3MBTL1 (0.43) ELANEL3MBTL1PDE4APDE4BPDE4C
SCHEMBL16703447 0.69 CNR1 (0.47) ELANEL3MBTL1PDE4APDE4BPDE4C
SCHEMBL800345 0.69 L3MBTL1 (0.36) ELANEL3MBTL1PDE4APDE4BPDE4C
SCHEMBL17461858 0.69 PDE4A (0.51) ELANEPDE4APDE4BPDE4CPDE4D
SCHEMBL10532885 0.68 ESR1 (0.40) L3MBTL1RETCNR1CNR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023098738-A1 COMPOUND CONTAINING OXADIAZOLE STRUCTURE AND PREPARATION METHOD THEREFOR AND USE THEREOF, AND FUNGICIDE 江苏中旗科技股份有限公司 2023-06-08 WO disclosed