Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | PNP | P00491 | 2/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16359959 | 1.00 | HINT1 (0.60) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL26630706 | 1.00 | HINT1 (0.60) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL26630708 | 1.00 | HINT1 (0.60) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL27351 | 0.93 | HINT1 (0.59) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL27352 | 0.93 | HINT1 (0.59) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL7614834 | 0.92 | HPGD (0.59) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL28805008 | 0.92 | HPGD (0.59) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL7614827 | 0.92 | HPGD (0.59) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL27659 | 0.92 | ADORA2A (0.58) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL27658 | 0.92 | ADORA2A (0.58) | HINT1HPGDNT5EADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122316-A2 | SPLICE SWITCH OLIGONUCLEOTIDE (SSO) MOLECULES FOR TARGETING β-CATENIN AND USES THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |