Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368234 | 0.86 | PARP10 (0.41) | PARP10PARP11MMP12MAPTGAA | |
| SCHEMBL2744551 | 0.79 | EGFR (0.47) | PARP10PARP11MAPTGAAPARP1 | |
| SCHEMBL6128272 | 0.79 | MEN1 (0.36) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL10060233 | 0.78 | PARP1 (0.44) | MAPTALDH1A1PARP1MEN1KMT2A | |
| SCHEMBL6128309 | 0.76 | ALDH1A1 (0.43) | MAPTGAAALDH1A1HSD17B10DYRK1B | |
| SCHEMBL16118883 | 0.76 | HTR2C (0.36) | MAPTPARP1MEN1KMT2A | |
| SCHEMBL20821122 | 0.76 | ABCC4 (0.34) | MAPTMEN1KMT2A | |
| SCHEMBL6128344 | 0.75 | CA12 (0.38) | MAPTALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL8560344 | 0.75 | GAA (0.67) | MAPTGAAALDH1A1HSD17B10MEN1 | |
| SCHEMBL20821138 | 0.74 | MAPT (0.32) | MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098880-A1 | FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |