Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21380293 | 0.83 | DGAT1 (0.33) | CYP2C9CYP2C19 | |
| SCHEMBL21380292 | 0.83 | DGAT1 (0.33) | CYP2C9CYP2C19 | |
| SCHEMBL21380420 | 0.83 | DGAT1 (0.33) | CYP2C9CYP2C19 | |
| SCHEMBL3623187 | 0.80 | HDAC8 (0.41) | HDAC8HDAC6TSHRCYP2C9CYP2C19 | |
| SCHEMBL15541922 | 0.79 | KDM4E (0.38) | MITFKMT2ANR1H2NR1H3 | |
| SCHEMBL3126066 | 0.79 | KDM4E (0.38) | MITFKMT2ANR1H2NR1H3 | |
| SCHEMBL30726182 | 0.79 | KDM4E (0.38) | MITFKMT2ANR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL15542195 | 0.78 | KDM4E (0.37) | MITFKMT2ANR1H2NR1H3 | |
| SCHEMBL25250387 | 0.77 | BTK (0.41) | MITFTSHRSMN1; SMN2 | |
| SCHEMBL21061620 | 0.77 | PI4KB (0.37) | HDAC8HDAC6KMT2AABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098880-A1 | FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |