Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 2/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL27643616 | 0.96 | HCAR2 (0.41) | HCAR2ERN1KDM4ENAPRTALDH1A1 | |
| SCHEMBL626513 | 0.80 | SIRT3 (0.42) | KDM4EALDH1A1TDP1MAPTHPGD | |
| SCHEMBL31132417 | 0.80 | SIRT3 (0.42) | KDM4EALDH1A1TDP1MAPTHPGD | |
| SCHEMBL15023500 | 0.80 | HCAR2 (0.43) | HCAR2ERN1KDM4ENAPRTALDH1A1 | |
| SCHEMBL68960 | 0.77 | KDM4E (0.47) | HCAR2ERN1KDM4ENAPRTALDH1A1 | |
| SCHEMBL25171290 | 0.77 | HCAR2 (0.40) | HCAR2ERN1KDM4ENAPRTALDH1A1 | |
| SCHEMBL1667344 | 0.76 | HPGD (0.47) | HCAR2KDM4ENAPRTALDH1A1TDP1 | |
| SCHEMBL1344662 | 0.76 | SMN1; SMN2 (0.48) | HCAR2ERN1KDM4ENAPRTALDH1A1 | |
| SCHEMBL29364820 | 0.76 | HPGD (0.47) | HCAR2KDM4ENAPRTALDH1A1TDP1 | |
| SCHEMBL758324 | 0.76 | NAPRT (0.48) | HCAR2ERN1KDM4ENAPRTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119056253-A | Chlorine-resistant high-flux nanofiltration membrane prepared based on grafting modification and preparation method thereof | 浙江理工大学桐乡研究院有限公司 | 2024-12-03 | — | — | CN | claimed |
| EP-0015772-A1 | N-(2-((acylaminoacylamino or aminoacylamino)phenyl)-4-hydroxy-5-pyrimidinylcarbonyl)cephalosporin compounds, processes for their production, and compositions containing the same | WARNER-LAMBERT COMPANY (US) | 1980-09-17 | — | — | EP | claimed |
| CN-119056253-A | Chlorine-resistant high-flux nanofiltration membrane prepared based on grafting modification and preparation method thereof | 浙江理工大学桐乡研究院有限公司 | 2024-12-03 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-104744446-B | Heteroaryl compound and its application in drug | 广东东阳光药业有限公司 | 2019-06-25 | — | — | CN | disclosed |
| EP-2758059-B1 | SUBSTITUTED PYRIMIDINES | MERCK SHARP & DOHME (US) | 2018-10-24 | — | — | EP | disclosed |
| EP-2758058-B1 | SUBSTITUTED PYRIMIDINES | MERCK SHARP & DOHME (US) | 2017-04-26 | — | — | EP | disclosed |
| EP-2560655-B1 | SUBSTITUTED PYRIMIDINES | MERCK SHARP & DOHME (US) | 2016-08-24 | — | — | EP | disclosed |
| EP-1486489-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| US-9096527-B2 | TRPM8 antagonists and their use in treatments | AMGEN INC. (US) | 2015-08-04 | — | — | US | disclosed |
| EP-0711757-A1 | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists | F. Hoffmann-La Roche AG (CH) | 1996-05-15 | — | — | EP | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4315933-A | PENICILLINS | WARNER-LAMBERT COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4311699-A | Aminoacid derivatives of cephalosporin compounds | HASKELL THEODORE H | 1982-01-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4267180-A | PENICILLINS AND DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| EP-0015772-A1 | N-(2-((acylaminoacylamino or aminoacylamino)phenyl)-4-hydroxy-5-pyrimidinylcarbonyl)cephalosporin compounds, processes for their production, and compositions containing the same | WARNER-LAMBERT COMPANY (US) | 1980-09-17 | — | — | EP | disclosed |