Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | ASPH | Q12797 | 5/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 4/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31358930 | 0.86 | KDM4E (0.37) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL29952052 | 0.85 | HCAR2 (0.40) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL9632777 | 0.85 | HCAR2 (0.40) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL9630633 | 0.85 | HCAR2 (0.40) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL758324 | 0.80 | NAPRT (0.48) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL4717959 | 0.78 | NAPRT (0.47) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL629032 | 0.77 | HCAR2 (0.44) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL2575802 | 0.77 | HCAR2 (0.44) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL30978924 | 0.77 | HCAR2 (0.44) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL352483 | 0.77 | SPR (0.45) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142826-B2 | Substitution-type electroless gold plating solution containing purine or pyrimidine-based compound having carbonyl oxygen and substitution-type electroless gold plating method using the same | MK CHEM & TECH CO., LTD (KR) | 2021-10-12 | — | — | US | claimed |
| US-20200095685-A1 | SUBSTITUTION-TYPE ELECTROLESS GOLD PLATING SOLUTION CONTAINING PURINE OR PYRIMIDINE-BASED COMPOUND HAVING CARBONYL OXYGEN AND SUBSTITUTION-TYPE ELECTROLESS GOLD PLATING METHOD USING THE SAME | MK CHEM & TECH CO., LTD (KR) | 2020-03-26 | — | — | US | claimed |
| US-8968711-B2 | Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process | L'OREAL (FR) | 2015-03-03 | — | — | US | claimed |
| US-20100272660-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT | L'OREAL (FR) | 2010-10-28 | — | — | US | claimed |
| US-20100239509-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS | L'OREAL (FR) | 2010-09-23 | — | — | US | claimed |
| EP-0332314-B1 | SOLVENT EXTRACTION PROCESS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-23 | — | — | EP | claimed |
| US-4961856-A | CONTACTING AQUEOUS SOLUTION CONTAINING PALLADIUM WITH SOLUTION OF SUBSTITUTED HETEROCYCLIC RING COMPOUND | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-09 | — | — | US | claimed |
| EP-0332314-A2 | Solvent extraction process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-13 | — | — | EP | claimed |
| US-11730737-B2 | Aldose reductase inhibitors and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-08-22 | — | — | US | disclosed |
| US-11730737-B2 | Aldose reductase inhibitors and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-08-22 | — | — | US | disclosed |
| CN-116322616-A | Hair lightening compositions providing damage protection and sensory benefits and methods of use | 欧莱雅 | 2023-06-23 | — | — | CN | disclosed |
| EP-4124620-A1 | ALDOSE REDUCTASE INHIBITORS AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 2023-02-01 | — | — | EP | disclosed |
| US-11559474-B2 | Hair lightening compositions and methods of use | L'OREAL (FR) | 2023-01-24 | — | — | US | disclosed |
| US-11529349-B2 | Aldose reductase inhibitors and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-12-20 | — | — | US | disclosed |
| US-4961856-A | CONTACTING AQUEOUS SOLUTION CONTAINING PALLADIUM WITH SOLUTION OF SUBSTITUTED HETEROCYCLIC RING COMPOUND | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-09 | — | — | US | disclosed |
| EP-0332314-A2 | Solvent extraction process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-13 | — | — | EP | disclosed |
| EP-0112617-B1 | PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| US-4581220-A | CURED RESIDUE OF ZIRCONIUM SOLUTION | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1986-04-08 | — | — | US | disclosed |
| US-4576815-A | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1986-03-18 | — | — | US | disclosed |
| EP-0112617-A1 | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11529349-B2 | Aldose reductase inhibitors and uses thereof | ALDOA, AKR1B1, AKR1C2 | KDM4E 1917/4885ALDH1A1 18/4885MAPT 1238/4885 |
| US-20100239509-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS | CUTA, SUCLG1, KRT18 | KDM4E 2504/4885ALDH1A1 1901/4885MAPT 2575/4885 |
| US-20100272660-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT | ACMSD, CUTA, PCCA | KDM4E 1109/4885ALDH1A1 1510/4885MAPT 3115/4885 |
| US-11559474-B2 | Hair lightening compositions and methods of use | TYR, ALAD, CYBA | KDM4E 2585/4885ALDH1A1 448/4885MAPT 3104/4885 |
| US-11730737-B2 | Aldose reductase inhibitors and uses thereof | ALDOA, AKR1B1, AKR1C2 | KDM4E 1917/4885ALDH1A1 18/4885MAPT 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.