Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | PDE4A | P27815 | 2/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269841 | 0.85 | NPC1 (0.48) | RAB9ANPC1PDE4APDE4BPDE4C | |
| SCHEMBL12330284 | 0.82 | RAB9A (0.52) | RAB9ANPC1PDE4APDE4BPDE4C | |
| SCHEMBL12260596 | 0.82 | PDE4A (0.53) | RAB9ANPC1PDE4APDE4BPDE4C | |
| SCHEMBL15001727 | 0.80 | KMT2A (0.61) | RAB9ANPC1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12031170 | 0.79 | PDE4A (0.54) | RAB9ANPC1PDE4APDE4BPDE4C | |
| SCHEMBL5461438 | 0.79 | MAPT (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL20023067 | 0.79 | MRGPRX4 (0.44) | RAB9ANPC1PDE4APDE4BPDE4C | |
| SCHEMBL28012695 | 0.77 | NPC1 (0.65) | RAB9ANPC1PDE4APDE4BPDE4C | |
| SCHEMBL12330301 | 0.77 | NPC1 (0.70) | RAB9ANPC1TDP1ALDH1A1CASP3 | |
| SCHEMBL23367937 | 0.76 | RAB9A (0.61) | RAB9ANPC1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |