SCHEMBL25758174

SCHEMBL25758174

CC(C)CC(NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C(C)(C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CS)NC(=O)C(CO)NC(=O)C(C)NC(=O)c1ccccn1)C(=O)NC(CS)C(N)=O

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY5R Q15761 7/20 0.41
▸ NPY4R P50391 7/20 0.41
▸ NPY1R P25929 6/20 0.41
▸ NPY2R P49146 4/20 0.41
▸ TFPI P10646 2/20 0.41
▸ KISS1R Q969F8 1/20 0.40
▸ OPRM1 P35372 4/20 0.39
▸ OPRK1 P41145 4/20 0.39
▸ IL23R Q5VWK5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25759233 0.96 NPY5R (0.39) NPY5RNPY4RNPY1RNPY2RTFPI
SCHEMBL25758263 0.95 TFPI (0.40) NPY5RNPY4RNPY1RNPY2RTFPI
SCHEMBL25758366 0.93 NPY4R (0.37) NPY5RNPY4RNPY1RNPY2RTFPI
SCHEMBL24155349 0.80 NPY4R (0.45) NPY5RNPY4RNPY1RNPY2RKISS1R
SCHEMBL25759551 0.80 NPY4R (0.45) NPY5RNPY4RNPY1RNPY2RKISS1R
SCHEMBL25758506 0.79 NPY4R (0.44) NPY5RNPY4RNPY1RNPY2R
SCHEMBL29659738 0.75 NPY4R (0.44) NPY5RNPY4RNPY1RNPY2R
SCHEMBL25758758 0.75 NPY4R (0.54) NPY5RNPY4RNPY1RNPY2R
SCHEMBL32690565 0.74 NPY4R (0.51) NPY5RNPY4RNPY1RNPY2R
SCHEMBL30811145 0.74 NPY4R (0.47) NPY5RNPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210939-A1 CYCLIC PEPTIDE COMPOUNDS AND METHODS OF USE VITEK, MICHAEL PETER 2023-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210939-A1 CYCLIC PEPTIDE COMPOUNDS AND METHODS OF USE VIP, NPPA, IAPP NPY5R 67/4885NPY4R 118/4885NPY1R 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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