Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 10/20 | 0.40 |
| ▸ | SRC | P12931 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 6/20 | 0.35 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | TEK | Q02763 | 5/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12369391 | 0.85 | RET (0.53) | RETSRCLCKKDRTEK | |
| SCHEMBL24296940 | 0.74 | SRC (0.49) | RETSRCLCKKDRTEK | |
| SCHEMBL19684532 | 0.71 | SRC (0.44) | RETSRCLCKKDRTEK | |
| SCHEMBL25467969 | 0.71 | SRC (0.44) | RETSRCLCKKDRTEK | |
| SCHEMBL25753719 | 0.68 | RET (0.46) | RETSRCLCKKDRTEK | |
| SCHEMBL12369390 | 0.68 | PDE2A (0.33) | — | |
| SCHEMBL21178862 | 0.67 | SRC (0.50) | RETSRCLCKKDRTEK | |
| SCHEMBL16361030 | 0.66 | LRRK2 (0.39) | RETSRCLCKKDREGFR | |
| SCHEMBL24970475 | 0.66 | RET (0.44) | RETSRCLCKKDRTEK | |
| SCHEMBL21178871 | 0.64 | RET (0.53) | RETSRCLCKKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | RET 3660/4885SRC 4269/4885LCK 4179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.