Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143867 | 0.83 | CYP1A2 (0.39) | GAAMAPTPTPN7CYP2D6TSHR | |
| SCHEMBL27768922 | 0.76 | GAA (0.56) | GAAMAPTEGLN1PTPN7 | |
| SCHEMBL4999605 | 0.76 | GAA (0.56) | GAAMAPTPTPN7 | |
| SCHEMBL27375830 | 0.73 | GAA (0.45) | GAAMAPT | |
| SCHEMBL27515096 | 0.73 | GAA (0.45) | GAAMAPT | |
| SCHEMBL6472971 | 0.73 | EGLN1 (0.43) | GAAMAPTGRIA2EGLN1CYP2D6 | |
| SCHEMBL27462590 | 0.72 | GAA (0.44) | GAAMAPT | |
| SCHEMBL30402802 | 0.72 | ITGB1 (0.35) | — | |
| SCHEMBL21739383 | 0.70 | KCNH2 (0.33) | TSHRMAPK1 | |
| SCHEMBL24448407 | 0.70 | GAA (0.45) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109926-A1 | SPIROOXINDOLE COMPOUND AND USE THEREOF IN PREPARATION OF PROTEASE INHIBITOR AS ANTIVIRAL DRUG | 南京药石科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |