Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3641806 | 0.98 | EGLN1 (0.42) | MAPK1SLC13A3EGLN1OR51E2ALDH1A1 | |
| SCHEMBL6426591 | 0.84 | ALDH1A1 (0.46) | EGLN1ALDH1A1TSHR | |
| SCHEMBL1272326 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL29060484 | 0.80 | PHF8 (0.46) | MAPK1SLC13A3EGLN1OR51E2ALDH1A1 | |
| SCHEMBL28167499 | 0.80 | OR51E2 (0.46) | MAPK1SLC13A3EGLN1OR51E2ALDH1A1 | |
| SCHEMBL3776646 | 0.79 | EGLN1 (0.55) | MAPK1SLC13A3EGLN1OR51E2ALDH1A1 | |
| SCHEMBL27719570 | 0.78 | HAO1 (0.32) | OR51E2 | |
| SCHEMBL19899419 | 0.75 | MAPK1 (0.37) | MAPK1SLC13A3EGLN1OR51E2ALDH1A1 | |
| SCHEMBL4738804 | 0.73 | OR51E2 (0.48) | MAPK1SLC13A3EGLN1OR51E2ALDH1A1 | |
| SCHEMBL5792150 | 0.73 | OR51E2 (0.48) | MAPK1SLC13A3EGLN1OR51E2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609616-B2 | Strontium-containing compounds for use in the prevention or treatment of necrotic bone conditions | OSTEOLOGIX A/S (DK) | 2013-12-17 | — | — | US | disclosed |
| US-20110269675-A1 | STRONTIUM-CONTAINING COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF NECROTIC BONE CONDITIONS | OSTEOLOGIX A/S | 2011-11-03 | — | — | US | disclosed |
| EP-1732575-B1 | STRONTIUM-CONTAINING COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF NECROTIC BONE CONDITIONS | OSTEOLOGIX AS (DK) | 2010-12-29 | — | — | EP | disclosed |
| US-20080167513-A1 | Strontium-Containing Compounds for Use in the Prevention or Treatment of Necrotic Bone Conditions | OSTEOLOGLX A/S (DK) | 2008-07-10 | — | — | US | disclosed |
| EP-1732575-A1 | STRONTIUM-CONTAINING COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF NECROTIC BONE CONDITIONS | Osteologix A/S (DK) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005082385-A1 | STRONTIUM-CONTAINING COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF NECROTIC BONE CONDITIONS | OSTEOLOGIX A/S (DK) | 2005-09-09 | — | — | WO | disclosed |