Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405843 | 1.00 | PDPK1 (0.46) | PDPK1PDE3BPDE3AHTR2CHTR2B | |
| SCHEMBL16865685 | 0.96 | PDPK1 (0.43) | PDPK1PDE3BPDE3AHTR2CHTR2B | |
| SCHEMBL21626531 | 0.89 | PDPK1 (0.40) | PDPK1PDE3BPDE3AHTR2CHTR2B | |
| SCHEMBL12158617 | 0.82 | KDM4E (0.39) | HTR2CKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL17807493 | 0.82 | PDE3B (0.45) | PDE3BPDE3AHTR2CKDM4ELMNA | |
| SCHEMBL24795597 | 0.80 | MAPK14 (0.40) | KDM4E | |
| SCHEMBL16866588 | 0.80 | HTR2B (0.48) | HTR2CHTR2BHTR5AKDM4ENPC1 | |
| SCHEMBL15684012 | 0.80 | MAP4K4 (0.44) | PDPK1HTR2CKDM4ENPC1RAB9A | |
| SCHEMBL12158630 | 0.78 | KDM4E (0.45) | HTR2CKDM4ENPC1RAB9AKMT2A | |
| SCHEMBL24795236 | 0.77 | KDM4E (0.41) | HTR2CTDO2KDM4EADORA2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200024294-A1 | Organic metal compound and organic light-emitting device | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2020-01-23 | — | — | US | disclosed |
| US-10183013-B2 | Cyclic sulfonamide containing derivatives as inhibitors of hedgehog signaling pathway | NANT HOLDINGS IP, LLC (US) | 2019-01-22 | — | — | US | disclosed |
| US-10164199-B2 | Organic metal compound and organic light-emitting device employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2018-12-25 | — | — | US | disclosed |
| US-20180175309-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2018-06-21 | — | — | US | disclosed |
| US-20180175309-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2018-06-21 | — | — | US | disclosed |
| US-20170135992-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | NANT HOLDINGS IP, LLC | 2017-05-18 | — | — | US | disclosed |
| US-20170135992-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | NANT HOLDINGS IP, LLC | 2017-05-18 | — | — | US | disclosed |
| US-9499539-B2 | Cyclic sulfonamide containing derivatives as inhibitors of hedgehog signaling pathway | NANTBIOSCIENCE, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160164007-A1 | ORGANIC METAL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2016-06-09 | — | — | US | disclosed |
| US-20160164007-A1 | ORGANIC METAL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2016-06-09 | — | — | US | disclosed |
| US-20150299190-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | NANT HOLDINGS IP, LLC | 2015-10-22 | — | — | US | disclosed |
| US-8722207-B2 | Organometallic compound, organic electroluminescence device and composition employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2014-05-13 | — | — | US | disclosed |
| CN-102952162-A | Organometallic compound, and organic electroluminescent device and composition comprising the same | IND TECH RES INST | 2013-03-06 | — | — | CN | disclosed |
| US-20130033171-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-02-07 | — | — | US | disclosed |
| CN-102911211-A | Organometallic compound and organic electroluminescent device comprising the same | IND TECH RES INST | 2013-02-06 | — | — | CN | disclosed |
| US-20110285275-A1 | ORGANOMETALLIC COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND COMPOSITION EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-11-24 | — | — | US | disclosed |
| US-7445857-B2 | Organometallic complex and organic electroluminescent devices utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-11-04 | — | — | US | disclosed |
| US-7445857-B2 | Organometallic complex and organic electroluminescent devices utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-11-04 | — | — | US | disclosed |
| US-20070237981-A1 | Organometallic complex and organic electroluminescent devices utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2007-10-11 | — | — | US | disclosed |
| US-20070237981-A1 | Organometallic complex and organic electroluminescent devices utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180175309-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME | C1S, C1R, C9 | PDPK1 4479/4885PDE3B 4770/4885PDE3A 4786/4885 |
| US-10183013-B2 | Cyclic sulfonamide containing derivatives as inhibitors of hedgehog signaling pathway | SMO, SHH, SOS1 | PDPK1 715/4885PDE3B 1363/4885PDE3A 1209/4885 |
| US-20110285275-A1 | ORGANOMETALLIC COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND COMPOSITION EMPLOYING THE SAME | OR10J3, ORC3, C1S | PDPK1 2816/4885PDE3B 4639/4885PDE3A 4778/4885 |
| US-20160164007-A1 | ORGANIC METAL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME | C5, C9, C1S | PDPK1 4210/4885PDE3B 4806/4885PDE3A 4847/4885 |
| US-20130033171-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | ALDH16A1, ALDH1A1, ALDH2 | PDPK1 588/4885PDE3B 2135/4885PDE3A 2335/4885 |
| US-20150299190-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | SMO, SHH, SOS1 | PDPK1 715/4885PDE3B 1363/4885PDE3A 1209/4885 |
| US-20170135992-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | SMO, SHH, SOS1 | PDPK1 715/4885PDE3B 1363/4885PDE3A 1209/4885 |
| US-10164199-B2 | Organic metal compound and organic light-emitting device employing the same | C5, C9, C1S | PDPK1 4210/4885PDE3B 4806/4885PDE3A 4847/4885 |
| US-20200024294-A1 | Organic metal compound and organic light-emitting device | ORC3, C1S, C1R | PDPK1 4201/4885PDE3B 4785/4885PDE3A 4817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.