Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319559 | 1.00 | PKM (0.54) | PKMKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL5478099 | 0.98 | HTT (0.55) | PKMKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL9347786 | 0.98 | HTT (0.55) | PKMKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL9406236 | 0.98 | HTT (0.55) | PKMKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL10393841 | 0.98 | HTT (0.55) | PKMKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL9406241 | 0.98 | HTT (0.55) | PKMKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL10450410 | 0.98 | HTT (0.55) | PKMKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL9347776 | 0.98 | HTT (0.55) | PKMKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL5478101 | 0.98 | HTT (0.55) | PKMKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL9347924 | 0.95 | PKM (0.50) | PKMKMT2AHTTMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2275868-A | — | — | None | — | — | JP | disclosed |
| US-9273247-B2 | Substituted amino alcohols as chiral dopants | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20140228591-A1 | SUBSTITUTED AMINO ALCOHOLS AS CHIRAL DOPANTS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2014-08-14 | — | — | US | disclosed |
| US-8497261-B2 | 3-aminocaprolactam compounds for treating inflammatory disorders | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2013-07-30 | — | — | US | disclosed |
| US-8048335-B2 | Cholesteric liquid crystal composition | CHISSO CORPORATION (JP) | 2011-11-01 | — | — | US | disclosed |
| EP-1781299-B1 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE ENTPR LTD (GB) | 2010-12-22 | — | — | EP | disclosed |
| US-20100292213-A1 | Anti-Inflammatory Agents | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-11-18 | — | — | US | disclosed |
| CN-101029015-B | 3,4-difluaryl mercaptan ester liquid crystal compound | XI AN MODERN CHEMISTRY INST | 2010-10-06 | — | — | CN | disclosed |
| US-20100086506-A1 | CHOLESTERIC LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 2010-04-08 | — | — | US | disclosed |
| US-7691845-B2 | Anti-inflammatory agents | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-04-06 | — | — | US | disclosed |
| US-4642199-A | Novel liquid crystal compounds and liquid crystal compositions containing same | CHISSO CORPORATION (JP) | 1987-02-10 | — | — | US | disclosed |
| US-4637897-A | Nematic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-01-20 | — | — | US | disclosed |
| US-4632515-A | Heterocyclically substituted ethanes and their use in liquid crystal materials and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1986-12-30 | — | — | US | disclosed |
| EP-0164721-A2 | Novel liquid crystal compound and liquid crystal composition containing same | Chisso Corporation (JP) | 1985-12-18 | — | — | EP | disclosed |
| US-4552684-A | ANTHRAOXAZOLE OR ANTHRATHIAZOLE DYES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-11-12 | — | — | US | disclosed |
| EP-0152697-A1 | Heterocyclically substituted ethanes and their use in liquid crystal materials and devices | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1985-08-28 | — | — | EP | disclosed |
| US-4518226-A | TEMPERATURE, LIQUID CRYSTALS | KABUSHIKI KAISHA SUWA SEIKOSHA (JP) | 1985-05-21 | — | — | US | disclosed |
| US-4452718-A | Pyridazines | HOFFMANN-LA ROCHE INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4419262-A | Pyridazines | HOFFMANN-LA ROCHE INC. (US) | 1983-12-06 | — | — | US | disclosed |
| US-4113647-A | ELECTRO-OPTIC DISPLAY DEVICE | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100086506-A1 | CHOLESTERIC LIQUID CRYSTAL COMPOSITION | CYP46A1, NR1H3, NR1H4 | PKM 4055/4885KMT2A 3595/4885HTT 3618/4885 |
| US-20100292213-A1 | Anti-Inflammatory Agents | TNF, IL1RN, IL1R1 | PKM 2854/4885KMT2A 4579/4885HTT 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.