Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.83 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.83 |
| ▸ | ACHE | P22303 | 1/20 | 0.80 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.80 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30611354 | 1.00 | HTR1A (0.83) | HTR1ASLC6A4ACHESLC6A2SLC6A3 | |
| SCHEMBL25244597 | 0.98 | HTR1A (0.83) | HTR1ASLC6A4ACHESLC6A2SLC6A3 | |
| SCHEMBL30611348 | 0.96 | HTR1A (0.83) | HTR1ASLC6A4ACHESLC6A2SLC6A3 | |
| SCHEMBL25762556 | 0.96 | HTR1A (0.83) | HTR1ASLC6A4ACHESLC6A2SLC6A3 | |
| SCHEMBL25765303 | 0.94 | HTR1A (0.77) | HTR1ASLC6A4ACHESLC6A2SLC6A3 | |
| SCHEMBL30320098 | 0.93 | SLC6A4 (0.82) | HTR1ASLC6A4ACHESLC6A2SLC6A3 | |
| SCHEMBL25762678 | 0.93 | SLC6A4 (0.82) | HTR1ASLC6A4ACHESLC6A2SLC6A3 | |
| SCHEMBL25293626 | 0.89 | HTR1A (0.77) | HTR1ASLC6A4ACHESLC6A2SLC6A3 | |
| SCHEMBL25290993 | 0.87 | HTR1A (0.76) | HTR1ASLC6A4ACHESLC6A2SLC6A3 | |
| SCHEMBL25285801 | 0.86 | HTR1A (0.81) | HTR1ASLC6A4ACHESLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116915-A1 | ACHE/SERT DUAL-TARGET INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 珠海市藤栢医药有限公司 | 2023-06-29 | — | — | WO | disclosed |