Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12663126 | 0.81 | MAOB (0.39) | PPARGPPARAMAOB | |
| SCHEMBL177781 | 0.81 | MAOB (0.39) | PPARGPPARAMAOB | |
| SCHEMBL177782 | 0.81 | MAOB (0.39) | PPARGPPARAMAOB | |
| SCHEMBL257663 | 0.79 | MAOB (0.41) | PPARGPPARAMAOB | |
| SCHEMBL12663125 | 0.79 | MAOB (0.41) | PPARGPPARAMAOB | |
| SCHEMBL12663131 | 0.79 | MAOB (0.41) | PPARGPPARAMAOB | |
| SCHEMBL29825561 | 0.78 | LIPE (0.53) | MAOB | |
| SCHEMBL1711426 | 0.78 | LIPE (0.53) | MAOB | |
| SCHEMBL12663154 | 0.78 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL12663157 | 0.76 | IGLV6-57 (0.45) | GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |