SCHEMBL2576469

SCHEMBL2576469

Fc1cc(F)cc(N2C=Cc3ccccc3C2)c1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.33
FFAR4 Q5NUL3 3/20 0.33
FFAR1 O14842 3/20 0.33
HDAC3 O15379 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B3 P37058 1/20 0.32
DRD2 P14416 1/20 0.31
DRD3 P35462 1/20 0.31
KCNH2 Q12809 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TAS1R2 Q8TE23 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27710876 0.85 PARP1 (0.34) PARP1HDAC3ALDH1A1TAS1R3TAS1R1
SCHEMBL15251305 0.83 PARP1 (0.33) PARP1HDAC3ALDH1A1TAS1R3TAS1R1
SCHEMBL30284584 0.80 NPC1 (0.44) PARP1HDAC3HSD17B3
SCHEMBL1553150 0.80 NPC1 (0.44) PARP1HDAC3HSD17B3
SCHEMBL28248906 0.80 MAPT (0.51) PARP1HDAC3ALDH1A1HSD17B3TAS1R3
SCHEMBL28153735 0.79 NPC1 (0.43) PARP1HDAC3HSD17B3
SCHEMBL1356606 0.79 NPC1 (0.43) PARP1HDAC3HSD17B3
SCHEMBL31612033 0.79 NPC1 (0.43) PARP1HDAC3HSD17B3
SCHEMBL30633069 0.79 NPC1 (0.43) PARP1HDAC3HSD17B3
SCHEMBL29809356 0.76 RAB9A (0.42) PARP1HDAC3ALDH1A1HSD17B3TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048537-B2 Cyclometalated transition metal complex and organic light emitting device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-11-01 US disclosed
US-20070184303-A1 Cyclometalated transition metal complex and organic light emitting device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-08-09 US disclosed