Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755617 | 0.78 | TDP1 (0.43) | TDP1CYP3A4ALDH1A1NPSR1ALOX15 | |
| SCHEMBL23331775 | 0.77 | ESR1 (0.47) | CYP3A4ALDH1A1ESR1ESR2MEN1 | |
| SCHEMBL2574194 | 0.76 | MEN1 (0.42) | TDP1CYP3A4ALDH1A1NPSR1ALOX15 | |
| SCHEMBL11063406 | 0.74 | CYP3A4 (0.39) | TDP1CYP3A4ALDH1A1NPSR1ALOX15 | |
| SCHEMBL28635021 | 0.73 | TDP1 (0.50) | TDP1CYP3A4ALDH1A1ESR1ESR2 | |
| SCHEMBL11080870 | 0.73 | KMT2A (0.43) | TDP1CYP3A4ALDH1A1NPSR1ALOX15 | |
| SCHEMBL9715912 | 0.72 | CYP3A4 (0.33) | TDP1CYP3A4ESR1ESR2 | |
| SCHEMBL14938874 | 0.72 | TDP1 (0.38) | TDP1CYP3A4ALDH1A1NPSR1ALOX15 | |
| SCHEMBL3305686 | 0.72 | CYP3A4 (0.38) | TDP1CYP3A4ALDH1A1NPSR1ALOX15 | |
| SCHEMBL32679515 | 0.71 | CYP3A4 (0.47) | TDP1CYP3A4ALDH1A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1312162-C | Organic phosphine compound with both hole and electron channel structure and its oxide and prepn process | UNIV FUDAN (CN) | 2007-04-25 | — | — | CN | claimed |
| CN-1706852-A | Organic phosphine compound with both hole and electron channel structure and its oxide and prepn process | UNIV FUDAN (CN) | 2005-12-14 | — | — | CN | claimed |
| EP-1466946-B1 | FLAME-RETARDANT RESIN COMPOSITION | POLYPLASTICS CO (JP) | 2011-11-09 | — | — | EP | disclosed |
| CN-1312162-C | Organic phosphine compound with both hole and electron channel structure and its oxide and prepn process | UNIV FUDAN (CN) | 2007-04-25 | — | — | CN | disclosed |
| US-7205346-B2 | halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants | POLYPLASTICS CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| CN-1706852-A | Organic phosphine compound with both hole and electron channel structure and its oxide and prepn process | UNIV FUDAN (CN) | 2005-12-14 | — | — | CN | disclosed |
| US-20040254270-A1 | Flame-retardant resin composition | POLYPLASTICS CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1466946-A1 | FLAME-RETARDANT RESIN COMPOSITION | Polyplastics Co., Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |