Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | PYGM | P11217 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25761495 | 0.88 | GAA (0.41) | GAANFKB1NFKB2RELAPIM1 | |
| SCHEMBL25767744 | 0.82 | DRD2 (0.38) | GAADRD2NFKB1NFKB2RELA | |
| SCHEMBL20263891 | 0.81 | GAA (0.40) | GAANFKB1NFKB2RELAKDM4E | |
| SCHEMBL25761428 | 0.80 | DRD2 (0.38) | GAADRD2NFKB1NFKB2RELA | |
| SCHEMBL20280041 | 0.80 | GAA (0.40) | GAANFKB1NFKB2RELAKDM4E | |
| SCHEMBL25760377 | 0.80 | GAA (0.41) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL29270803 | 0.79 | GAA (0.43) | GAANFKB1NFKB2RELAKDM4E | |
| SCHEMBL26962099 | 0.79 | GAA (0.44) | GAANFKB1NFKB2RELAKDM4E | |
| SCHEMBL25759562 | 0.79 | GAA (0.42) | GAANFKB1NFKB2RELAKDM4E | |
| SCHEMBL5735937 | 0.76 | GAA (0.42) | GAANFKB1NFKB2RELARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119210-A1 | NOVEL COMPOUND AS RIPK1 INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 제일약품주식회사 | 2023-06-29 | — | — | WO | disclosed |