SCHEMBL25770586

SCHEMBL25770586

Cc1ccc(N(c2ccc(C)c3ccccc23)c2ccc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)c3ccccc23)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.44
ALDH1A1 P00352 3/20 0.44
DHFR P00374 1/20 0.41
CYP1A2 P05177 5/20 0.41
TSHR P16473 2/20 0.38
KDM4E B2RXH2 2/20 0.37
MAPT P10636 1/20 0.37
PABPC1 P11940 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
NISCH Q9Y2I1 1/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
BRD4 O60885 1/20 0.35
CYP3A4 P08684 2/20 0.34
TYMP P19971 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25770446 0.86 CYP2A6 (0.38) CYP2A6ALDH1A1DHFRCYP1A2TSHR
SCHEMBL12744236 0.83 CYP2A6 (0.54) CYP2A6ALDH1A1CYP1A2TSHRHPGD
SCHEMBL25770594 0.83 CYP1A2 (0.39) CYP2A6DHFRCYP1A2KDM4EMAPT
SCHEMBL25776465 0.83 CYP2A6 (0.35) CYP2A6ALDH1A1CYP1A2TSHRHPGD
SCHEMBL25776516 0.83 ALDH1A1 (0.33) CYP2A6ALDH1A1SIGMAR1
SCHEMBL25776585 0.83 ALDH1A1 (0.33) CYP2A6ALDH1A1KDM4EMAPTPABPC1
SCHEMBL25770587 0.81 IKBKB (0.36) CYP2A6ALDH1A1CYP1A2TSHRSMN1; SMN2
SCHEMBL12914248 0.81 NISCH (0.42) CYP2A6ALDH1A1CYP1A2TSHRKDM4E
SCHEMBL12914244 0.81 NISCH (0.42) CYP2A6ALDH1A1CYP1A2TSHRKDM4E
SCHEMBL13908268 0.81 CYP1A2 (0.43) CYP2A6ALDH1A1CYP1A2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212334-A1 POLYMER, ELECTROLUMINESCENCE MATERIAL, ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-07-06 US disclosed