Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 7/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470457 | 0.88 | MARS1 (0.45) | CNR1CNR2 | |
| SCHEMBL14089383 | 0.88 | CNR2 (0.43) | CNR1CNR2 | |
| SCHEMBL176542 | 0.83 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL176910 | 0.83 | CNR2 (0.56) | CNR1CNR2 | |
| SCHEMBL300388 | 0.82 | CNR2 (0.46) | CNR1CNR2 | |
| SCHEMBL176432 | 0.82 | CNR2 (0.57) | CNR1CNR2 | |
| SCHEMBL176961 | 0.81 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL13745542 | 0.81 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL4912464 | 0.80 | CNR2 (0.48) | CNR1CNR2 | |
| SCHEMBL14089543 | 0.79 | CNR2 (0.49) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | disclosed |
| WO-2008115705-A2 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-09-25 | — | — | WO | disclosed |