SCHEMBL25771902

SCHEMBL25771902

Cn1c(CCCCCCc2cccc(Cl)c2)c(C(=O)N2CC(CC(=O)O)C2)c2cc(Cl)cnc21

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ OXER1 Q8TDS5 16/20 0.41
▸ TACR1 P25103 1/20 0.36
▸ CYP4F2 P78329 1/20 0.36
▸ CYP4A11 Q02928 1/20 0.36
▸ SCD5 Q86SK9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25771841 0.90 OXER1 (0.40) OXER1TACR1
SCHEMBL25771840 0.86 OXER1 (0.55) OXER1
SCHEMBL25771786 0.85 OXER1 (0.38) OXER1TACR1CYP4F2CYP4A11
SCHEMBL25780754 0.84 OXER1 (0.46) OXER1
SCHEMBL25780755 0.82 THRB (0.37) OXER1
SCHEMBL25780753 0.79 OXER1 (0.41) OXER1
SCHEMBL25781025 0.79 KMT2A (0.35) OXER1TACR1
SCHEMBL25770330 0.79 OXER1 (0.66) OXER1
SCHEMBL25771839 0.76 OXER1 (0.54) OXER1
SCHEMBL25776161 0.75 OXER1 (0.45) OXER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023115203-A1 OXER1 ANTAGONISTS AND USES THEREOF FAIRHAVEN PHARMACEUTICALS INC. (CA) 2023-06-29 — — WO disclosed
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